Gilbert’s Syndrome what is it and what you can do about it?

Gilbert’s syndrome (GS)

GS is another possible reason for IBS. If you have this genetic predisposition, it means an enzyme in your liver is genetically lacking or impaired. Bilirubin is formed in the liver by the breakdown of hemoglobin cells, and is an orange-yellow color (commonly known as red blood cell breakdown)

Bilirubin needs to be conjugated with another component in the liver in order to be eliminated wither via urine or feces. If you have this genetic predisposition and you are on a diet that is not appropriate for you, as well as under stress and/or taking any extra medication, then you might get a build-up of bilirubin in the blood stream. If you have GS, then you may notice a yellowing of the white part of your eyes, or in some cases yellowing of the skin. This condition can be worsened by stress, drinking alcohol, eating too much sugar, too much caffeine, chocolate, too many nuts, fried food, junk food, fizzy drinks, having a menstrual cycle, or taking drugs or medications, paracetamol or the contraceptive pill, or any other form of hormones, can all increase your bilirubin level leading to a possible increase of allergies. This condition is usually non-harmful, if is controlled well with the diet and your diet is adjusted appropriately i.e. low in toxins.

It can, however, become a problem if there is an overload of toxins, with an increase jaundice and possibly brain fog. I have this condition in my family and it can become dangerous if not enough attention to the diet and lifestyle is paid. The mild hyperbilirubinemia can have an antioxidant effect, as it is a scavenger of reactive oxygen species. This reduces the oxidative stress in your cells and blood stream, hence reducing damaging of your cell, and vascular cell membrane, hence reducing arteriosclerosis, which is a problem in ischemic heart disease and diabetic vascular complications.  

GS can be diagnosed by a doctor who will test the total unconjugated bilirubin, and if it is high for no other medical reasons, then you know that you have it and if is higher than 25 might be causing your IBS symptoms.

My dietary suggestions with GS are to drink plenty of water (up to 2 liters a day or till your urine is clear in color instead of yellow), eat meals with lipid in that, as that will reduce bilirubin level, as it needs fats or lipid to be excreted. Do not fast for long. Eat something or another every 3 to 4 hours (fish is really good, eggs as well), with plenty of vegetables, olive oil, avocadoes, and glutathione supporting vitamins for the support of the liver detox, as well as take dietary supplements such as probiotics and glutamine to repair your intestinal tract. Sunlight breaks down excess bilirubin from your skin naturally so it is worth getting some sunshine as well.

In people with normal liver detox of bilirubin, sometimes that is achieved by given statins, which will inhibit the glucuronidation liver pathway and hence increase the anti-oxidant effect of mild hyperbilirubinemia

The above has been taken from my book “Clinical experience of Irritable Bowel Syndrome” by Maria Esposito – sold on amazon click here to buy

© Maria Esposito BSc (Hons) R-Nutritional Therapist – NAET for allergies – R-Craniosacral Therapist – NLP – Angel Guide Certified – Mindfulness –

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